Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4073
rs4073
0.020 GeneticVariation BEFREE This meta-analysis demonstrated a suggestive result that people who carried the risk A allele of the IL-8 rs4073 polymorphism may be more sensitive to acute pancreatitis. 31340771

2019

dbSNP: rs10273639
rs10273639
0.030 GeneticVariation BEFREE Our findings suggested that rs7057398, rs12688220 and rs10273639 polymorphisms could be used to identify individuals at an elevated susceptibility to acute pancreatitis in Caucasians. 31163246

2020

dbSNP: rs12688220
rs12688220
0.020 GeneticVariation BEFREE Our findings suggested that rs7057398, rs12688220 and rs10273639 polymorphisms could be used to identify individuals at an elevated susceptibility to acute pancreatitis in Caucasians. 31163246

2020

dbSNP: rs7057398
rs7057398
0.020 GeneticVariation BEFREE Our findings suggested that rs7057398, rs12688220 and rs10273639 polymorphisms could be used to identify individuals at an elevated susceptibility to acute pancreatitis in Caucasians. 31163246

2020

dbSNP: rs11209026
rs11209026
0.010 GeneticVariation BEFREE Epistasis analysis revealed that AP susceptibility was increased by interaction between <i>IL23R</i> rs11209026 and <i>TNF</i> rs1800629 (p = 1.205 × 10<sup>-5</sup>; OR<sub>interaction</sub> = 4.031). 31044631

2019

dbSNP: rs1800629
rs1800629
TNF
0.010 GeneticVariation BEFREE Epistasis analysis revealed that AP susceptibility was increased by interaction between <i>IL23R</i> rs11209026 and <i>TNF</i> rs1800629 (p = 1.205 × 10<sup>-5</sup>; OR<sub>interaction</sub> = 4.031). 31044631

2019

dbSNP: rs213950
rs213950
0.010 GeneticVariation BEFREE Therefore, the aim of our study was to determine the functional importance of common cystic fibrosis transmembrane conductance regulator variations IVS8-poly T, R117H, and M470V for the severity of acute pancreatitis. 30132293

2019

dbSNP: rs78655421
rs78655421
0.010 GeneticVariation BEFREE Therefore, the aim of our study was to determine the functional importance of common cystic fibrosis transmembrane conductance regulator variations IVS8-poly T, R117H, and M470V for the severity of acute pancreatitis. 30132293

2019

dbSNP: rs10273639
rs10273639
0.030 GeneticVariation BEFREE Meta-analyses of all AP patients depicted significant (p-value < 0.05) associations for rs10273639 (odds ratio (OR) 0.88, 95% confidence interval (CI) 0.81-0.97, p-value 0.01), rs7057398 (OR 1.27, 95% CI 1.07-1.5, p-value 0.005), and rs12688220 (OR 1.32, 95% CI 1.12-1.56, p-value 0.001). 29884332

2018

dbSNP: rs12688220
rs12688220
0.020 GeneticVariation BEFREE Meta-analyses of all AP patients depicted significant (p-value < 0.05) associations for rs10273639 (odds ratio (OR) 0.88, 95% confidence interval (CI) 0.81-0.97, p-value 0.01), rs7057398 (OR 1.27, 95% CI 1.07-1.5, p-value 0.005), and rs12688220 (OR 1.32, 95% CI 1.12-1.56, p-value 0.001). 29884332

2018

dbSNP: rs7057398
rs7057398
0.020 GeneticVariation BEFREE Meta-analyses of all AP patients depicted significant (p-value < 0.05) associations for rs10273639 (odds ratio (OR) 0.88, 95% confidence interval (CI) 0.81-0.97, p-value 0.01), rs7057398 (OR 1.27, 95% CI 1.07-1.5, p-value 0.005), and rs12688220 (OR 1.32, 95% CI 1.12-1.56, p-value 0.001). 29884332

2018

dbSNP: rs1800896
rs1800896
0.030 GeneticVariation BEFREE IL-10 gene rs1800896 polymorphism increases the risk of AP. 29310417

2017

dbSNP: rs4251961
rs4251961
0.010 GeneticVariation BEFREE IL1RN -1129T>C (rs4251961) genotypes might be associated with a significant increase of AP risk in a Korean ethnic group. 29117667

2018

dbSNP: rs1805017
rs1805017
0.010 GeneticVariation BEFREE These results demonstrated that the LP-PLA2 gene polymorphisms, V279F and R92H, may be associated with susceptibility to and severity of AP. 28332853

2017

dbSNP: rs76863441
rs76863441
0.010 GeneticVariation BEFREE These results demonstrated that the LP-PLA2 gene polymorphisms, V279F and R92H, may be associated with susceptibility to and severity of AP. 28332853

2017

dbSNP: rs497078
rs497078
0.010 GeneticVariation BEFREE The aim of the study was to determine the relationship between the presence of p.G60 = polymorphism (c.180C > T; rs497078) CTRC and the incidence together with the clinical course of acute pancreatitis (AP). 28095786

2017

dbSNP: rs1052571
rs1052571
0.010 GeneticVariation BEFREE CASP9 Phe136Leu/Phe136Phe SNPs (heterozygotes) increases the risk for mild AP (odds ratio, 3.616; 95% confidence interval, 1.151-11.364; P < 0.05), whereas the homozygotic genotype of CASP9 Ala28Val decreases risk for mild AP (odds ratio, 0.296; 95% confidence interval, 0.091-0.963; P < 0.05). 27984487

2017

dbSNP: rs1132312
rs1132312
0.010 GeneticVariation BEFREE CASP9 Phe136Leu/Phe136Phe SNPs (heterozygotes) increases the risk for mild AP (odds ratio, 3.616; 95% confidence interval, 1.151-11.364; P < 0.05), whereas the homozygotic genotype of CASP9 Ala28Val decreases risk for mild AP (odds ratio, 0.296; 95% confidence interval, 0.091-0.963; P < 0.05). 27984487

2017

dbSNP: rs121912654
rs121912654
0.010 GeneticVariation BEFREE The presence of GSTM1 is associated with increased susceptibility for AP, and the GSTP1 Val105Ile SNP is associated with an increased risk for AP in men. 27984487

2017

dbSNP: rs142907823
rs142907823
0.010 GeneticVariation BEFREE CASP9 Phe136Leu/Phe136Phe SNPs (heterozygotes) increases the risk for mild AP (odds ratio, 3.616; 95% confidence interval, 1.151-11.364; P < 0.05), whereas the homozygotic genotype of CASP9 Ala28Val decreases risk for mild AP (odds ratio, 0.296; 95% confidence interval, 0.091-0.963; P < 0.05). 27984487

2017

dbSNP: rs1490931437
rs1490931437
0.010 GeneticVariation BEFREE CASP9 Phe136Leu/Phe136Phe SNPs (heterozygotes) increases the risk for mild AP (odds ratio, 3.616; 95% confidence interval, 1.151-11.364; P < 0.05), whereas the homozygotic genotype of CASP9 Ala28Val decreases risk for mild AP (odds ratio, 0.296; 95% confidence interval, 0.091-0.963; P < 0.05). 27984487

2017

dbSNP: rs1695
rs1695
0.010 GeneticVariation BEFREE The presence of GSTM1 is associated with increased susceptibility for AP, and the GSTP1 Val105Ile SNP is associated with an increased risk for AP in men. 27984487

2017

dbSNP: rs778574118
rs778574118
0.010 GeneticVariation BEFREE The presence of GSTM1 is associated with increased susceptibility for AP, and the GSTP1 Val105Ile SNP is associated with an increased risk for AP in men. 27984487

2017

dbSNP: rs10273639
rs10273639
0.030 GeneticVariation BEFREE We confirmed a robust association of polymorphism rs10273639 at PRSS1-PRSS2 with AP in the Russian population. 27846138

2017

dbSNP: rs1800896
rs1800896
0.030 GeneticVariation BEFREE In a dominant model, we found that the GA+AA genotype of IL-10 rs1800896 was associated with an elevated risk of acu</span>te pancreatitis (OR = 1.51, 95%CI = 1.05-2.18). 26634555

2015